GLP-1 Medication Cost Comparisons

GLP-1 medications are among the most expensive branded prescription drugs in the United States, with list prices ranging from roughly $900 to $1,350 per month before insurance. Actual out-of-pocket cost depends on payer type, plan formulary tier, prior authorization requirements, manufacturer savings cards, and — for weight-loss indications — whether the drug is covered at all. Medicare Part D does not cover GLP-1 drugs when prescribed solely for weight loss under current statute, though coverage applies when the same drug is prescribed for type 2 diabetes or FDA-approved cardiovascular risk reduction. Commercial insurance coverage varies widely. The comparisons below break down list price, typical insurance co-pay ranges, manufacturer savings-card eligibility, and the specific coverage differences between otherwise-similar drugs — for example, Wegovy vs Ozempic, same molecule but different billing codes.